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From my experience, just the opposite. I had many lows from regular
insulin, mainly due to the long time constant that exists with regular.
Humilog only lasts a couple of hours, and works faster. This means that it
doesn’t stay around and cause problems later; also the basal time constants
are very short, and tend to operate more in real time.
I have had virtually no problems with lows except for occasions when I
miscalculate the bolus.
But, since the Humilog wears out in 2 hours, some long lasting carbs will
not be compensated for by the Humilog, which is why mixing with some regular
may be a useful idea. But, I use the square wave feature to compensate for
long lasting carbs, and this works quite well. Also, testing after 2 hours
is mandatory to catch this long lasting problem; even a test after four
hours is often necessary to be sure.
Hi Kathy:
answer # 1 - Regular insulin takes about 1 hour to really kick into gear
whereas Humalog takes 15 minutes. Regular peaks in 4-6 hours after
administration.
Humalog is metabolized out in about 1 hour. There are advantages and
disadvantages with both. However, Humalog is proving more successful for
those of us who use it in our pumps since we can address high bg s faster and
get a quicker response. So depending on our particular needs, you’ll find
some of us a bit more challenged and using combinations. It’s not always
safe and can lead to some unexpected lows, so keep that in mind.
and talk to Frank - Fac11 to find out what to do about your ID….Joan:)
April 26th, 2004 at 6:46 am
From my experience, just the opposite. I had many lows from regular
insulin, mainly due to the long time constant that exists with regular.
Humilog only lasts a couple of hours, and works faster. This means that it
doesn’t stay around and cause problems later; also the basal time constants
are very short, and tend to operate more in real time.
I have had virtually no problems with lows except for occasions when I
miscalculate the bolus.
But, since the Humilog wears out in 2 hours, some long lasting carbs will
not be compensated for by the Humilog, which is why mixing with some regular
may be a useful idea. But, I use the square wave feature to compensate for
long lasting carbs, and this works quite well. Also, testing after 2 hours
is mandatory to catch this long lasting problem; even a test after four
hours is often necessary to be sure.
April 27th, 2004 at 11:23 pm
Hi Kathy:
answer # 1 - Regular insulin takes about 1 hour to really kick into gear
whereas Humalog takes 15 minutes. Regular peaks in 4-6 hours after
administration.
Humalog is metabolized out in about 1 hour. There are advantages and
disadvantages with both. However, Humalog is proving more successful for
those of us who use it in our pumps since we can address high bg s faster and
get a quicker response. So depending on our particular needs, you’ll find
some of us a bit more challenged and using combinations. It’s not always
safe and can lead to some unexpected lows, so keep that in mind.
and talk to Frank - Fac11 to find out what to do about your ID….Joan:)
April 28th, 2004 at 4:45 am
David, this sounds like a mirror of my experience.
fp