Comments on: HbA1c - HGbA1c

By: roy_1600

roy_1600 — Mon, 12 Jan 2004 18:58:51 +0000

ok Jan..like Les said…his description of testing for glucose what very
precise and succinct…HgA1C - glycosylated hemoglobin works on percentages
for diabetics: good control 7.5%-11.4% (we all know these #s and it depends
on the lab) moderate control 11.5-15% (miserable in my estimation); poor
control > 15%.
its the percentage of glucose saturated in the red blood cell.- evaluates
control over a 3-4 month period
Fructosamine- shorter time span
C-peptide inactive amino acid reside degradation product of proinsulin.
Formed as a byproduct during the endogenous conversion of proinsulin to
insulin in the beta cells…means you have to be producing insulin to make
it….could go on…best reference I use for school is "Laboratory Tests and
Diagnostic Procedures by Chernecky and Berger" pub. Saunders - can get it
thru Amazon.com….Joan

By: damian150

damian150 — Fri, 09 Jan 2004 11:31:47 +0000

Someone said that the test is an AVERAGE of BGs. I’m wondering if 50 and
250 — let’s say it would run that way awhile, of course, for non-pumpers — would the test result be 150? or the equivalent. I also was told by a
nurse that one of the tests was protein binding.
Jan

By: roy_1600

roy_1600 — Thu, 08 Jan 2004 17:26:44 +0000

Jan explain what you are asking a bit more so I can help…Joan

By: mui400

mui400 — Wed, 07 Jan 2004 09:50:21 +0000

The glycated Hemoglobin test is a test which measures the percentage of
hemoglobin in the blood that is glycated(has glucose attached to it), which
indicates the level of blood glucose control over the past few
months.Glycated hemoglobins (in lab talk hemoglobin is abbreviated as Hgb or
Hb or sometimes just H as when you see on ER the Dr order an H & H which
stands for hemoglobin and hematocrit).Glycated hgbs or glycohemoglobins are
composed of linkages between hemoglobin and various sugars.They are formed
slowly and irreversibly in the body through a process called non-enzymatic
glycation. During this process, glucose in the bloodstream enters circulating
red blood cells.Inside the red blood cell, the glucose molecule attaches to
the hemoglobin and remains there for about 4 months (the usual life-span of a
red blood cell).As a general rule, a Hemoglobin A1c of 8% would correspond to
an average blood sugar of 180 (plasma calibrated)..likewise a 7% would be
150, a 6% would be 120 .There is also another method called the Fructosamine
test which gives you a picture of what your sugars were over the past 2-3

weeks..Also just for the record your ideal HgbA1c test should be determined
solely by your Dr because each lab does the test differently resulting in
different "normal for the diabetic values"..To sum up then, a HgbA1c of 7
might be different for you compared to another diabetic who gets a 7. Go by
what your Dr says.Hope this helps..Les