Mixing Insulin in the pump

has anyone tried mixing Regular and Humalog in your pump? If so how has it
worked for you? At what ratio do u mix it?

Thanks

Frank

12 Responses to “Mixing Insulin in the pump”

  1. rodney_800 Says:

    Frank, why would you mix Humolog with another regular, they are both
    regulars. I know Humolog is much faster absorbing, but if you mixed you
    wouldn’t know the ratio you were getting in relation to when you pumped in.

    Gail

    At 12:15 PM 5/6/99 -0400, you wrote:
    > has anyone tried mixing Regular and Humalog in your pump? If so how has
    >it worked for you? At what ratio do u mix it? Thanks Frank

  2. kristan_180 Says:

    Why would anyone want to do this? I have used Humilog in the pump
    since its inception, and find it remarkable. My a1c is down a full
    point, I have no more dangerous Bgs so why would anyone want to use
    regular in its place?

    David

    Frank wrote:

    > has anyone tried mixing Regular and Humalog in your pump? If so how
    > has it worked for you? At what ratio do u mix it? Thanks Frank

  3. antoinette_5 Says:

    The reason why I am thinking about this is because the Humalog sometimes
    burns very fast especially since my digestion has slowed down due to
    Gastroparesis. People do mix Humalog and Regular, the ratio is How much
    Humalog to Regular. Some people use 4 units of Humalog to 1 unit of humalog.
    I was just wondering if anyone has tried and have they had any success.

  4. clair4 Says:

    Dear Frank..I would not advise mixing insulin..humalog is the best
    formulation invented so far..as far as your gastroparesis problem might I
    suggest that you experiment with the square wave bolus feature on your
    pump..I read about this in an issue of Self-Management ..you could check with
    your Dr about it..Good Luck..Leslie

  5. kristan_180 Says:

    From my experience, mixing the two insulins would be counterproductive. I get
    such good results with Humilog that I would not want the danger of introducing a
    longer lasting insulin in the mix. But, the short lifetime is a serious
    problem, and I routinely test BG two hours after any meal. A long lasting carb
    (e.g., pasta) can boost the BG after the Humilog wears out. The square wave
    bolus available in the Minimed 507 is very useful for counteracting this effect,
    and I use it when I know a carb will be around for more than two hours.
    David

    Frank wrote:

  6. rodney_800 Says:

    What is this square wave bolus? I have it heard it mentioned before on
    this list. Is it the same as an alternate bolus? I have a Mini-Med 506.
    When do you use the alternative bolus.
    Gail

  7. antoinette_5 Says:

    It is okay Gail, some people have been mixing the 2 insulins because they
    feel that Humalog can clog and plus it can give u more protection against a
    severe high blood sugar because when Humalog clogs or if u have a set
    problem u tend to go high very fast.
    A square wave bolus is a feature that was put on the Minimed 507, it allows
    u to give a bolus over a longer period of time. I have used the feature and
    continue to. Instead of taking the dose all at once u can program it over an
    half an hour or up to 2 hours.

  8. antoinette_5 Says:

    I agree David, I tend to test 2 hours after I eat to. The only thing is
    everyone is individual, what might work well for you may not work well for
    the next person. I do not know if I would take the risk of mixing 2 types
    but I wanted to know if any one has and how there experiences have been.
    Thanks David

  9. kristan_180 Says:

    The square wave bolus distributes the selected bolus value over a specified
    number of hours. For example, I often take a standard 5 unit bolus and a
    square wave 5 unit bolus spread over 4 hours. This amounts to a 10 unit
    bolus spread over four hours with an up front 5 units followed by 2.5
    units/hour for four hours. Minimed introduced this feature in the 507 as
    many people (me included) were simulating a square wave bolus in the 506 using
    a temporary basal value. This is awkward to enter, however, and the square
    wave feature makes it easy. I first learned about the sq. wave concept from
    the UCSF diabetes teaching center in San Francisco. I think (not sure) that
    the new edition of pumping insulin has some stuff about it. Anyway, when
    using Humilog it is a great idea, due to the short lifetime of the insulin.

    David

    GAIL DARLING wrote:

  10. kristan_180 Says:

    I would consider using regular insulin just as dangerous as the fear of the
    short life of the Humilog, as regular builds up in your system and lasts longer,
    resulting in unexpected lows. Since I started using Humilog I have had NO
    dangerous lows; I used to have one a month using regular insulin in the pump.
    Now, no more!!
    David

    Frank wrote:

  11. rodney_800 Says:

    Frank, with your gastroparesis I am surprised you test two hours after a
    meal. I also have gastro. and my meal is just in the process of digesting,
    so if I take a bg two hours after eating it doesn’t really tell me
    anything. I am really having trouble now, I eat six small meals a day, so
    it seems I always have food digesting and I find it difficult to find a
    time I can get an accurate bg.
    Gail

  12. kristan_180 Says:

    You suggest that your BG’s are not accurate 2 hr. after…they probably are
    accurate, but meaningless. I don’t know much about your particular problem,
    but
    I would tend to just take BG’s every 2 hr. until I found the number that made
    sense. What we really need is a continuous monitor, like the proposed
    glucowatch (which looks unlikely at this date)…
    David

    GAIL DARLING wrote:

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